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10.1038/s41569-023-00849-3 124 VellaA.ShahP.BasuR.BasuA.HolstJ
Importantly, 100 mg/kg cinchonine ameliorated hepatic steatosis and fibrosis in NASH mice
While it has been studied over one to two years in clinical trials, there is limited data beyond that time frame, especially regarding: Long-term metabolic effects Nutrient deficiencies due to reduced food intake Potential changes to gut microbiota Dependency on the drug to maintain weight loss Potential changes to gut microbiota Some clinicians have voiced concern that stopping Ozempic can result in rapid weight regain and the return of previous metabolic issues
No statistically significant differences were detected among the groups with respect to primordial and antral follicle counts (Fig
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